
These 15 Large Companies Are Proudly Rooted in Missouri
Missouri is home to thousands of businesses, but these 15 are the biggest and proudly call the Show-Me State home.
Zippia recently ranked the top 100 businesses in Missouri, and these 15 stand out as the largest. Some of these names are likely familiar, while others might surprise you.

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However, what they all have in common is that they’re based right here in Missouri.
15 Large Missouri-Based Companies in Missouri
According to Zippia, the largest companies in Missouri that you probably didn't even know are all based in the Show-Me State.
Gallery Credit: Samantha Barnes
Rounding Out the Top 20
Among the top companies are:
- Cerner, based in Kansas City, is a healthcare tech giant.
- Amdocs, headquartered in Chesterfield, specializes in software and services.
- Monsanto is an agrochemical and agricultural biotech company in St. Louis.
- The University of Missouri System is based in Columbia.
- EarthGrains Baking Companies, a leader in the food production industry, is based in St. Louis.
These companies are always looking for new employees. So, if you're thinking about making a career change or just curious about job opportunities, these businesses could be a great place to start.
Counties with the highest unemployment in Missouri
Stacker compiled a list of the counties with the highest unemployment in Missouri using data from the Bureau of Labor Statistics. Counties are ranked by unemployment rate in June.
Gallery Credit: Stacker
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