Maybe you have seen this sign as you approach the Bayview Bridge:

 

I originally thought this was in anticipation of the Moonlight Ride for Hunger, but that takes place Saturday evening.

The MO-168 overpass at Palmyra is being replaced. In order to completely remove the old bridge, US-24 / US-61 will be closed at the north end of Palmyra for 24-hours. According to the MODOT Web site:

...all lanes of U.S. Route 61/24 will be closed for approximately 24 hours overnight from 1:00 a.m. on Sunday, August 6, through 1:00 a.m. on Monday, August 7," Haeffner added. After 1:00 a.m. August 7, U.S. Route 61 will have at least one lane open to traffic in each direction at the overpass throughout the project.

Detours will be marked. If I were you...I'd just stay on the Illinois side this Sunday.